Just did the synthesis ending. Given the choices I've made throughout ME2 and 3, I don't think that either of the other choices work for me. Destroying all synthetics, while that would eliminate the reapers, would also kill EDI and the geth. I personally wouldn't feel right doing that considering that Shep helps both of them gain a sense of self and individuality. Sentencing them to death just doesn't feel right. As for controlling the reapers...that doesn't seem like the option for me either. Synthesis seems the most likely to give a chance for lasting peace. And in my opinion, that's the only option that doesn't screw the galaxy when the Mass Relays blow up. Working together, I could see the organics and synthetics rebuilding the relay network. As for the Normandy's fate...she didn't seem too badly beat up on landing. Probably Joker's fine touch. And assuming the entire crew survives, then I can't think of any reason that they couldn't get the ship up and going again. Not to mention that if the Normandy were wrecked beyond all possibility of repair, EDI would be screwed anyways.
And Shep? I don't understand how the only endings where Shepard survives are destruction endings. If you destroy all synthetic life, then that would definitely kill Shepard since he/she is at least partly synthetic thanks to the Lazarus Project. Personally, I am a bit curious about my squadmates. Though the whole thing during the charge towards the beam seemed a bit too...convenient.